The Bush Lab works at the interface of analytical and biophysical sciences. We develop mass spectrometry and ion mobility spectrometry technologies that provide novel insights into structures and assembly of biomolecular machines and biotherapeutics, and apply these technologies to targets that are heterogeneous, dynamic, and interact with complex chemical matrixes. […]
Elyse is a PhD candidate in Dr. Nicolas Lehrbach’s lab at Fred Hutch Cancer Center. She is investigating how the mechanisms and regulation of ubiquitin-mediated protein degradation affect cellular function as we age. She uses C. elegans as a whole-animal model to combine complex genetic analysis to physiological readouts. […]
Dr. Frost is currently as a postdoctoral fellow in the Kane lab. She is studying epigenetic patterns, including DNA methylation and histone modifications, and their relationship with frailty and sex differences in aging. This builds upon her thesis work completed in the Heinrich Lab at the University of California, Riverside, which was rooted in unraveling […]
