The Bush Lab works at the interface of analytical and biophysical sciences. We develop mass spectrometry and ion mobility spectrometry technologies that provide novel insights into structures and assembly of biomolecular machines and biotherapeutics, and apply these technologies to targets that are heterogeneous, dynamic, and interact with complex chemical matrixes. […]
Understanding of molecular recognition, and interactions that play important roles in aging and disease Dr. Klevit is the Edmond H. Fischer/WRF Endowed Chair in Biochemistry, an Adjunct Professor of Pharmacology, and Adjunct Professor of Chemistry. Current research in Dr. Klevit’s laboratory is directed towards an understanding of fundamental molecular recognition events involved in the process […]
Lindsey is a PhD candidate in the Bush lab. Lindsey Ulmer’s research involves developing novel crosslinking mass spectrometry methods through working with the Bush Lab in the UW chemistry department and applying these methods to study small heat shock proteins (sHSPs). sHSPs are chaperones that prevent aging associated protein aggregation. Using the reagent benzoylphenylalanine, she […]