UW Medicine

Michael Kiflezghi

Michael Kiflezghi

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Mr. Kiflezghi is a graduate student in the M3D Ph.D. program and pre-doctoral trainee in the Biological Mechanisms of Healthy Aging Training Program. He is performing his Ph.D. thesis studies in the Kaeberlein Lab, where he has developed and applied novel technology for identifying small molecule inhibitors of the mechanistic target of rapamycin (mTOR). As mTOR is a central regulator of aging, novel mTOR inhibitors are of high interest for basic and translational use to study aging and improve healthy longevity. He has applied these methods to a library of FDA approved compounds and, in addition to putative mTOR inhibitors, has identified compounds with previously undescribed antifungal and respiratory inhibitory properties.