UW Medicine

Brandon Berry

Brandon Berry

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Dr. Brandon Berry is a postdoctoral researcher in the Kaeberlein laboratory. His research focuses on how aging and metabolism are linked. Brandon is interested in how mitochondria, the powerhouses of cells, contribute to and modulate aging. He uses novel tools to precisely control mitochondria to better understand the fundamentals of healthy aging and metabolism. Brandon […]

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Jason Bielas

Jason Bielas

Titles

Associate Member, Translational Research Program, Fred Hutchinson Cancer Research Center
Affiliate Association Professor, Lab Medicine and Pathology

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Role of DNA mutation in aging and cancer Dr. Bielas is an Associate Member in the Translational Research Program at the Fred Hutchinson Cancer Research Center, and an Affiliate Associate Professor in the UW Department of Lab Medicine and Pathology. He has a long-standing interest in the relationships between aging, mutagenesis, and cancer. His past […]

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Alessandro Bitto

Alessandro Bitto

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Acting Instructor of Lab Medicine and Pathology

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Dr. Bitto is an Acting Instructor in the Department of Lab Medicine and Pathology. His research is focused on understanding the interaction between biological aging, mitochondrial function, and metabolic disease. Dr. Bitto was a BMHA post-doctoral fellow on the Genetic Approaches to Aging Training Grant from 2013-2016 and is the recipient of a post-doctoral research […]

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Anna Gillespie

Anna Gillespie

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Assistant Professor

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The Gillespie Lab strives to understand how the neural mechanisms underlying memory processes degrade over the course of healthy aging and in the context of neurodegenerative disease. The lab uses in vivo electrophysiology to record simultaneously from hundreds of hippocampal neurons in rats as they learn and perform complex memory-dependent tasks. We use advanced computational […]

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Matt Kaeberlein

Matt Kaeberlein

Titles

Former Director, Healthy Aging and Longevity Research Institute
Former Director, Biological Mechanisms of Healthy Aging Training Program
Co-Director, UW Nathan Shock Center of Excellence in the Basic Biology of Aging
Co-Director, Dog Aging Project
Professor of Pathology
Adjunct Professor of Genome Sciences
Adjunct Professor of Oral Health Sciences

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Dr. Kaeberlein’s research interests are focused on biological mechanisms of aging in order to facilitate translational interventions that promote healthspan and improve quality of life. He has published more than 200 scientific papers, has been recognized by several prestigious awards, and has Fellow status in the American Association for the Advancement of Science (AAAS), the […]

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C. Dirk Keene

C. Dirk Keene

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Associate Professor of Lab Medicine and Pathology

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Dr. Keene received his education at the University of Nevada, Las Vegas (B.S. in Cell and Molecular Biology) and the University of Minnesota (M.D. and Ph.D. in Neuroscience). His post-graduate medical training in Anatomic Pathology and Neuropathology was at the University of Washington where he earned a faculty position in Neuropathology. Currently, Dr. Keene is […]

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Scott Kennedy

Scott Kennedy

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Associate Professor of Lab Medicine and Pathology

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Dr. Kennedy is an Associate Professor in the Department of Laboratory Medicine and Pathology. He has a strong interest in the role of the fidelity mechanisms that cells employ to maintain genetic information and the ways these mechanisms are involved in diseases of aging. Research in the Kennedy lab focuses on developing and using Next-Generation […]

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Bernard Khor

Bernard Khor

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Affiliate Assistant Professor

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Dr. Khor’s lab is focused on understanding healthy aging through the lens of Down syndrome. Down syndrome is the most common chromosomal condition, and immune dysregulation significantly impairs the health of these individuals. This is manifest by predisposition to autoimmunity, susceptibility to infections and impaired vaccine response, amongst other features. Recent work in the lab […]

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David Marcinek

David Marcinek

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Professor of Radiology
Adjunct Professor of Bioengineering
Adjunct Professor of Lab Medicine and Pathology

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Dr. Marcinek joined the UW faculty in 2006. He has over 15 years of experience developing and applying innovative tools to study mitochondrial biology in chronic disease and aging. A main focus of his laboratory is to understand how age-related changes in mitochondrial function at the biochemical and organelle levels translate to changes in in […]

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Alexander Mendenhall

Alexander Mendenhall

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Assistant Professor of Lab Medicine and Pathology

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Dr. Mendenhall’s laboratory utilizes the nematode C. elegans to understand how and why genetically identical populations of cells and animals in the same environment age differently. How much and what kind of physiological variation is intrinsic/chance based, or is programmed and heritable? The lab takes the approach of directly observing events inside of living cells […]

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Daniel Promislow

Daniel Promislow

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Professor of Lab Medicine and Pathology
Professor of Biology

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Dr. Promislow studies natural genetic variation in aging and reproduction. His research is focused on aging in several systems – the fruit fly, companion dogs, and humans. He uses a diversity of approaches in his lab, including molecular and quantitative genetics, evolutionary theory, and systems biology to construct and analyze genetic and metabolomic networks. Among […]

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Peter Rabinovitch

Peter Rabinovitch

Titles

Professor, Department of Lab Medicine and Pathology
Joint Full Member, Fred Hutchinson Cancer Research Center

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Mitochondrial function and healthspan Peter Rabinovitch has served on the faculty of the Department of Lab Medicine and Pathology since 1983. He has been an active investigator in the biology of aging throughout his career, is the author of over 290 peer-reviewed publications, and is the founding director of the UW Nathan Shock Center of […]

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Shane Rea

Shane Rea

Titles

Associate Professor of Lab Medicine and Pathology

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C. elegans aging and healthspan extension Dr. Rea is an Associate Professor of Lab Medicine and Pathology. His laboratory utilizes the nematode Caenorhabditis elegans to probe the fundamental mechanisms of aging and mitochondrial dysfunction in humans. His research spanning three decades has revealed that nematode lifespan is controlled by a roughly equal mix of genetics, […]

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Rosana Risques

Rosana Risques

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Associate Professor of Lab Medicine and Pathology

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Genomic instability, cancer and aging The main focus of Dr. Risques’ research is the study of the molecular mechanisms that link genomic instability and aging. The main molecular alterations that her lab studies are telomere shortening, mitochondrial dysfunction, and age-related accumulation of somatic mutations.  She has published on comparative analyses of aging relating telomere length […]

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Ryan Rossner

Ryan Rossner

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Mr. Rossner is a graduate student in the M3D Ph.D. program studying the role of flavin-containing monooxygenase proteins in aging. He is performing his Ph.D. thesis under the mentorship of Dr. Kaeberlein. He was awarded a position on the Genetic Approaches of Aging Training Grant in 2016 and is currently a pre-doctoral trainee in the […]

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Shabnam Salimi

Shabnam Salimi

Titles

Acting Instructor

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Shabnam Salimi is a multidisciplinary scientist studying the mechanism of health span and lifespan. She uses clinical and laboratory tools to define health and multimorbidity as the rate of aging and functional decline and response to stress. Her works evolved around determining clinically and biologically meaningful algorithms that measure the rate of aging, “omics” that track healthspan […]

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Mariya Sweetwyne

Mariya Sweetwyne

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Assistant Professor

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Dr. Mariya Sweetwyne (she/her) is a Cell Biologist and Assistant Professor in the Department of Laboratory Medicine and Pathology (DLMP) in the UW School of Medicine. She earned a B.S. in Zoology and a B.S. in Cell and Molecular Biology from the University of Washington, followed by a Ph.D. in Cell and Molecular Biology from the University […]

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Paul Valdmanis

Paul Valdmanis

Titles

Associate Professor, Medical Genetics
Adjunct Associate Professor, Genome Sciences
Adjunct Associate Professor, Lab Medicine and Pathology

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Age-associated changes in synaptic non-coding RNAs Dr. Valdmanis joined the University of Washington as an Assistant Professor in 2017. His lab studies genetic risk factors for neurodegenerative diseases such as Alzheimer’s disease and Amyotrophic Lateral Sclerosis and gene therapy methods for therapeutic intervention. Through a series of studies focusing on long-read sequencing of the genome […]

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Jessica Young

Jessica Young

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Assistant Professor of Lab Medicine and Pathology

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Dr. Young joined the UW faculty in 2016 as an Assistant Professor in the Department of Lab Medicine and Pathology.  Her research goal is to understand the molecular and biochemical mechanisms underlying age-related disorders, with a particular focus on neurodegenerative disorders.  She has developed human stem cell models to further this line of research, as […]

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