Research Interest Research in the Morgan lab is focused on the role of mitochondrial function in disease, anesthetic response and aging. We primarily utilize mutants in C. elegans and mice to uncover genetic factors that modulate mitochondrial biochemistry. Selected publications Suthammarak W, Morgan PG, Sedensky MM. (2010). Mutations in mitochondrial complex III uniquely affect complex I in Caenorhabditis […]
Research Interest The Sedensky laboratory is using two model systems to understand multiple ramifications of mitochondrial dysfunction. Lifespan and neurodegeneration are two areas under active investigation. A long standing focus is understanding how mitochondrial function controls behavior in the volatile anesthetics. Selected publications Falk MJ, Kayser EB, Morgan PG, Sedensky MM. (2006). Mitochondrial complex I function […]
