UW Medicine

Bernard Khor

Bernard Khor

Titles

Affiliate Assistant Professor

Linked information

Khor Lab
bkhor(at)benaroyaresearch.org

Departments

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Roles

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Dr. Khor’s lab is focused on understanding healthy aging through the lens of Down syndrome. Down syndrome is the most common chromosomal condition, and immune dysregulation significantly impairs the health of these individuals. This is manifest by predisposition to autoimmunity, susceptibility to infections and impaired vaccine response, amongst other features. Recent work in the lab showed advanced immune aging of up to 17 years in people with Down syndrome, and ongoing work seeks to understand the underlying drivers. Mechanistic studies are expected to highlight novel therapeutic hypotheses to improve the immune health, not only of people with Down syndrome, but also subsets of the broader general population without Down syndrome.