- Associate Professor of Genome Sciences
Dr. Villen is an Associate Professor in the Department of Genome Sciences. She earned her PhD in Chemistry from the University of Barcelona. During her postdoc at Harvard Medical School she was involved in several technology developments that enabled the robust characterization of thousands of phosphorylation sites: from biochemical methods to mass spectrometry acquisition strategies to computational approaches for phosphoproteomics data analysis. These developments were broadly implemented in most proteomics labs and propelled phosphoproteomics into mainstream applications in biomedical research. Research in her laboratory focuses on the investigation of signaling pathways. She aims to understand the wiring diagram of the cell, with the ultimate goal of predicting and controlling cellular function. Age-related changes in regulation of signaling pathways is an important part of this work. She was a recipient of an NIH K99/R00 Pathway to Independence award and an Ellison Foundation New Scholar award, the latter further solidifying the applications of her work to the biology of aging. Her work in the field of proteomics has been recognized through the ASMS Research award in 2011 and the US HUPO Robert Cotter award in 2014. In 2015 and 2016, she was listed as “Highly cited researcher” by Thomson Reuters. Dr. Villen and Dr. Kaeberlein are co-PIs on two NIH R01 grants including an NIA funded Systems Biology of Aging project to study age-related degradation of the homeostatic signaling network in yeast.