Dr. Kaeberlein’s research interests are focused on biological mechanisms of aging in order to facilitate translational interventions that promote healthspan and improve quality of life. He has published more than 200 scientific papers, has been recognized by several prestigious awards, and has Fellow status in the American Association for the Advancement of Science (AAAS), the […]
Understanding aging through explainable machine learning The Lee lab seeks to develop explainable AI for life sciences. Explainable in this context means understanding which features drive the prediction. The Lee lab has been collaborating with the Kaeberlein lab to develop and apply machine learning to aging biology, with the initial goal of using noisy human […]
Applications of mass spectrometry in the biology of aging The focus of Dr. MacCoss’ laboratory is in the development and application of cutting edge mass spectrometry based technologies for the analysis of complex protein mixtures. His primary area of expertise is in protein biochemistry, nanoflow liquid chromatography, mass spectrometry instrumentation, and computational analysis of mass […]
Dr. Promislow studies natural genetic variation in aging and reproduction. His research is focused on aging in several systems – the fruit fly, companion dogs, and humans. He uses a diversity of approaches in his lab, including molecular and quantitative genetics, evolutionary theory, and systems biology to construct and analyze genetic and metabolomic networks. Among […]
Mitochondrial function and healthspan Peter Rabinovitch has served on the faculty of the Department of Lab Medicine and Pathology since 1983. He has been an active investigator in the biology of aging throughout his career, is the author of over 290 peer-reviewed publications, and is the founding director of the UW Nathan Shock Center of […]
Dr. Villen is an Associate Professor in the Department of Genome Sciences. She earned her PhD in Chemistry from the University of Barcelona. During her postdoc at Harvard Medical School she was involved in several technology developments that enabled the robust characterization of thousands of phosphorylation sites: from biochemical methods to mass spectrometry acquisition strategies […]
Dr. Young joined the UW faculty in 2016 as an Assistant Professor in the Department of Lab Medicine and Pathology. Her research goal is to understand the molecular and biochemical mechanisms underlying age-related disorders, with a particular focus on neurodegenerative disorders. She has developed human stem cell models to further this line of research, as […]