Departments
Roles
The Bruce Laboratory is focused on the development and application of proteomics technologies to provide new insight on biological function at the organelle, cellular and tissue levels. Our research has enabled new methods for quantitative interactome measurements and using our technologies we have begun exploration of concepts of systems structural biology. These studies reveal how […]
Titles
Departments
Bioengineering, Lab Medicine and Pathology, Radiology
Roles
BMHA Co-Director, BMHA Training Faculty, HALO Faculty, Shock Center Director, Shock Center Executive Committee
Dr. Marcinek joined the UW faculty in 2006. He has over 15 years of experience developing and applying innovative tools to study mitochondrial biology in chronic disease and aging. A main focus of his laboratory is to understand how age-related changes in mitochondrial function at the biochemical and organelle levels translate to changes in in […]
Departments
Roles
Dr. Pharaoh’s research is focused on the role of mitochondria in aging and disease using a multifaceted approach that integrates physiological, pharmaceutical, genetic, molecular, and mitochondrial bioenergetic techniques. Dr. Pharaoh’s research specifically focuses on the role of mitochondrial dysfunction in skeletal muscle and cardiac aging. Dr. Pharaoh received his Ph.D. from the University of Oklahoma […]
Departments
Roles
Bradley Ruple is a postdoctoral scholar in the Translational Bioenergetics Lab, training under David Marcinek. His research focuses on the molecular and physiological adaptations to exercise and nutritional interventions, with particular interest in skeletal muscle aging, mitochondrial dynamics, and cardiovascular health. Using a combination of clinical and translational approaches, he investigates how targeted interventions can […]
