UW Medicine

Nathan Shock Center Cores

The primary goal of the UW Nathan Shock Center is to maximize the impact of our Center’s services and outreach on the gerontological community nation- and world-wide.  To facilitate this overarching mission, our Center is organized into six Cores.

The Administrative and Program Enrichment Core provides leadership and facilitates communication, outreach, and training. A major focus of this Core is enhancing the impact of the Nathan Shock Centers by sponsorship and organization of pre-meetings and workshops at premier national scientific gatherings, including American Aging Association (AGE) and Gerontological Society of America (GSA) meetings. The Administrative and Program Enrichment Core also supports the Inter-Shock Center Geropathology Initiative.

The Research Development Core manages solicitation and selection of pilot awards. Pilot awards are targeted toward junior and new faculty at other institutions and generally provide up to $10,000 in services from one or more of our Resource Cores. Please see our most recent call for applications. Applicants are highly encouraged to contact Core leaders directly prior to submitting a pilot project proposal.

Our Resource Cores draw upon special expertise here at the University of Washington, while offering a spectrum of services that provide vertically integrated resources that 1) are of broad interest and relevance and can be widely utilized by aging investigators; 2) are innovative in ways not readily duplicated elsewhere; and 3) can be readily exported and made available to outside investigators.  The four Resource Cores are:

  • Protein Phenotypes of Aging (Proteomics)
  • Metabolite Phenotypes of Aging (Metabolomics)
  • Invertebrate Longevity and Healthspan
  • Artificial Intelligence and Bioinformatics

More information on each of our Cores and the services offered can be found on the individual Core webpages.

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Protein Phenotypes of Aging

The Protein Phenotypes of Aging Core is designed to provide the geroscience research community with access to state-of-the-art proteomics technologies. The Core has been at the forefront of developing technologies to perform large-scale targeted proteomics assays that generate near complete data matrices, accurate quantitation, and high reproducibility – even across multiple laboratories. The primary goal […]

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Metabolite Phenotypes of Aging

The Metabolite Phenotypes of Aging Core designed to provide state-of-the-art hardware and software tools to detect, identify and quantify aging-associated metabolites, to assist in the experimental design and statistical analysis of these metabolite profiles, and to develop novel analytical tools for more powerful analysis of metabolome studies. The Core has developed a variety of targeted […]

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Invertebrate Longevity and Healthspan

The Invertebrate Longevity and Healthspan Core assists investigators throughout the research community in quantifying a variety of longevity and healthspan measures in two of the major invertebrate model organisms: the budding yeast Saccharomyces cerevisiae and the nematode Caenorhabditis elegans. This is accomplished through direct collaboration, training and outreach, and the development and dissemination of new […]

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Artificial Intelligence

The AI Core brings state-of-the-art computational approaches, particularly in the area of AI, to support Center users and maximize the impact of the other Resource Cores.     Services Available: Consultation on AI or computationally intensive projects in aging research Collaboration on application of AI methods to important problems in aging research AI Workshop– The “AI meets […]

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Administrative Core

The Administrative Core provides effective leadership, administration and management of the Center. This Core supports the External Advisory Board of distinguished scientists who provide review and recommendations to the executive leadership of the Center and engages in outreach activities, including workshops, courses, lectures and symposia. The Administrative Core also oversees and ensures dissemination of Center […]

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Research Development

The Research Development Core provides support for researchers nation- and world-wide, most often junior faculty, to develop pilot data to aid in new project and career development.  This is assisted by granting of competitive awards for pilot project support for studies in the basic biology of aging, using the key resources provided by our Resource […]

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