UW Medicine

Treatments to rejuvenate the aging heart?

Tags: Heart failure, Scientific Press,

Caloric restriction is an anti-aging strategy that has been shown to extend lifespan and improve age-related diseases in animal models including non-human primates. Rapamycin, an FDA approved immune-suppressant drug, shares some similar anti-aging effects as caloric restriction.  However, most studies of the anti-aging effects of caloric restriction or Rapamycin have been long-term studies in which […]

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Anti-oxidant compound protects against heart failure in mice

Tags: Heart failure, Scientific Press,

A recent study in the Rabinovitch Lab has shown that an anti-oxidant compound, called SS-31, effectively protects against heart failure in mice, demonstrating a potential therapeutic value for human heart diseases. The study, Global proteomics and pathway analysis of pressure-overload-induced heart failure and its attenuation by mitochondrial-targeted peptides, was published in the September 2013 issue of Circulation: […]

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