UW Medicine

Maitreya Dunham

Maitreya Dunham

Titles

Professor of Genome Sciences

Departments

Roles

, , , ,

Aneuploidy, evolution, and aging. Dr. Dunham develops and applies genomic tools to study genome evolution and genetic variation in yeast and humans. She has a special interest in how gene and chromosome copy number variation contributes to adaptation, the mechanisms by which such variation arises, and the relationship between aneuploidy and aging.  They utilize the budding […]

Read More…


Warren Ladiges

Warren Ladiges

Titles

Professor of Comparative Medicine

Departments

Roles

, ,

Geropathology and mouse models in translational geroscience Dr. Ladiges is Professor of comparative medicine and Director of the Geropathology Research Network and the UW Nathan Shock Center Geropathology Resource. He has extensive experience in the pathobiological evaluation and modeling of mice for preclinical aging and intervention studies and has been a leader in the application […]

Read More…


Su-In Lee

Su-In Lee

Titles

Associate Professor, Paul G. Allen School of Computer Science & Engineering
Associate Professor, Genome Sciences

Departments

,

Roles

, , , ,

Understanding aging through explainable machine learning The Lee lab seeks to develop explainable AI for life sciences.  Explainable in this context means understanding which features drive the prediction.  The Lee lab has been collaborating with the Kaeberlein lab to develop and apply machine learning to aging biology, with the initial goal of using noisy human […]

Read More…


Michael MacCoss

Michael MacCoss

Titles

Professor of Genome Sciences

Departments

Roles

, , , , ,

Applications of mass spectrometry in the biology of aging The focus of Dr. MacCoss’ laboratory is in the development and application of cutting edge mass spectrometry based technologies for the analysis of complex protein mixtures. His primary area of expertise is in protein biochemistry, nanoflow liquid chromatography, mass spectrometry instrumentation, and computational analysis of mass […]

Read More…


David Marcinek

David Marcinek

Titles

Professor of Radiology
Adjunct Professor of Bioengineering
Adjunct Professor of Lab Medicine and Pathology

Departments

, ,

Roles

, , , ,

Dr. Marcinek joined the UW faculty in 2006. He has over 15 years of experience developing and applying innovative tools to study mitochondrial biology in chronic disease and aging. A main focus of his laboratory is to understand how age-related changes in mitochondrial function at the biochemical and organelle levels translate to changes in in […]

Read More…


Alexander Mendenhall

Alexander Mendenhall

Titles

Assistant Professor of Lab Medicine and Pathology

Departments

Roles

, , , ,

Dr. Mendenhall’s laboratory utilizes the nematode C. elegans to understand how and why genetically identical populations of cells and animals in the same environment age differently. How much and what kind of physiological variation is intrinsic/chance based, or is programmed and heritable? The lab takes the approach of directly observing events inside of living cells […]

Read More…


Daniel Promislow

Daniel Promislow

Titles

Professor of Lab Medicine and Pathology
Professor of Biology

Departments

,

Roles

, , , ,

Dr. Promislow studies natural genetic variation in aging and reproduction. His research is focused on aging in several systems – the fruit fly, companion dogs, and humans. He uses a diversity of approaches in his lab, including molecular and quantitative genetics, evolutionary theory, and systems biology to construct and analyze genetic and metabolomic networks. Among […]

Read More…


Peter Rabinovitch

Peter Rabinovitch

Titles

Professor, Department of Lab Medicine and Pathology
Joint Full Member, Fred Hutchinson Cancer Research Center

Departments

Roles

,

Mitochondrial function and healthspan Peter Rabinovitch has served on the faculty of the Department of Lab Medicine and Pathology since 1983. He has been an active investigator in the biology of aging throughout his career, is the author of over 290 peer-reviewed publications, and is the founding director of the UW Nathan Shock Center of […]

Read More…


Judit Villen

Judit Villen

Titles

Associate Professor of Genome Sciences

Departments

Roles

, , , ,

Dr. Villen is an Associate Professor in the Department of Genome Sciences. She earned her PhD in Chemistry from the University of Barcelona. During her postdoc at Harvard Medical School she was involved in several technology developments that enabled the robust characterization of thousands of phosphorylation sites: from biochemical methods to mass spectrometry acquisition strategies […]

Read More…


Jessica Young

Jessica Young

Titles

Assistant Professor of Lab Medicine and Pathology

Departments

Roles

, , , , , , ,

Dr. Young joined the UW faculty in 2016 as an Assistant Professor in the Department of Lab Medicine and Pathology.  Her research goal is to understand the molecular and biochemical mechanisms underlying age-related disorders, with a particular focus on neurodegenerative disorders.  She has developed human stem cell models to further this line of research, as […]

Read More…