UW Medicine

Maitreya Dunham

Maitreya Dunham

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Professor of Genome Sciences

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Aneuploidy, evolution, and aging. Dr. Dunham develops and applies genomic tools to study genome evolution and genetic variation in yeast and humans. She has a special interest in how gene and chromosome copy number variation contributes to adaptation, the mechanisms by which such variation arises, and the relationship between aneuploidy and aging.  They utilize the budding […]

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Matt Kaeberlein

Matt Kaeberlein

Titles

Director, Healthy Aging and Longevity Research Institute
Director, Biological Mechanisms of Healthy Aging Training Program
Co-Director, UW Nathan Shock Center of Excellence in the Basic Biology of Aging
Co-Director, Dog Aging Project
Professor of Pathology
Adjunct Professor of Genome Sciences
Adjunct Professor of Oral Health Sciences

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Dr. Kaeberlein’s research interests are focused on biological mechanisms of aging in order to facilitate translational interventions that promote healthspan and improve quality of life. He has published more than 200 scientific papers, has been recognized by several prestigious awards, and has Fellow status in the American Association for the Advancement of Science (AAAS), the […]

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Warren Ladiges

Warren Ladiges

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Professor of Comparative Medicine

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Geropathology and mouse models in translational geroscience Dr. Ladiges is Professor of comparative medicine and Director of the Geropathology Research Network and the UW Nathan Shock Center Geropathology Resource. He has extensive experience in the pathobiological evaluation and modeling of mice for preclinical aging and intervention studies and has been a leader in the application […]

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Su-In Lee

Su-In Lee

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Associate Professor, Paul G. Allen School of Computer Science & Engineering
Associate Professor, Genome Sciences

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Understanding aging through explainable machine learning The Lee lab seeks to develop explainable AI for life sciences.  Explainable in this context means understanding which features drive the prediction.  The Lee lab has been collaborating with the Kaeberlein lab to develop and apply machine learning to aging biology, with the initial goal of using noisy human […]

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Michael MacCoss

Michael MacCoss

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Professor of Genome Sciences

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Applications of mass spectrometry in the biology of aging The focus of Dr. MacCoss’ laboratory is in the development and application of cutting edge mass spectrometry based technologies for the analysis of complex protein mixtures. His primary area of expertise is in protein biochemistry, nanoflow liquid chromatography, mass spectrometry instrumentation, and computational analysis of mass […]

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Alexander Mendenhall

Alexander Mendenhall

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Assistant Professor of Lab Medicine and Pathology

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Dr. Mendenhall’s laboratory utilizes the nematode C. elegans to understand how and why genetically identical populations of cells and animals in the same environment age differently. How much and what kind of physiological variation is intrinsic/chance based, or is programmed and heritable? The lab takes the approach of directly observing events inside of living cells […]

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Daniel Promislow

Daniel Promislow

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Professor of Lab Medicine and Pathology
Professor of Biology

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Dr. Promislow studies natural genetic variation in aging and reproduction. His research is focused on aging in several systems – the fruit fly, companion dogs, and humans. He uses a diversity of approaches in his lab, including molecular and quantitative genetics, evolutionary theory, and systems biology to construct and analyze genetic and metabolomic networks. Among […]

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Peter Rabinovitch

Peter Rabinovitch

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Professor, Department of Lab Medicine and Pathology
Joint Full Member, Fred Hutchinson Cancer Research Center

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Mitochondrial function and healthspan Peter Rabinovitch has served on the faculty of the Department of Lab Medicine and Pathology since 1983. He has been an active investigator in the biology of aging throughout his career, is the author of over 290 peer-reviewed publications, and is the founding director of the UW Nathan Shock Center of […]

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Judit Villen

Judit Villen

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Associate Professor of Genome Sciences

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Dr. Villen is an Associate Professor in the Department of Genome Sciences. She earned her PhD in Chemistry from the University of Barcelona. During her postdoc at Harvard Medical School she was involved in several technology developments that enabled the robust characterization of thousands of phosphorylation sites: from biochemical methods to mass spectrometry acquisition strategies […]

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Lu Wang

Lu Wang

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Research Scientist

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Dr. Wang has served as a biostatistician in the UW EDGE Center, the UW Center on Human Development and Disability, and UW Nathan Shock Center of Excellence in the Basic Biology of Aging.  Dr. Wang has provided experimental design consultation, rigorous statistical analysis, and multi-omics data analyses (including transcriptomics, genomics, metabolomics, and proteomics)  to numerous […]

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Jessica Young

Jessica Young

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Assistant Professor of Lab Medicine and Pathology

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Dr. Young joined the UW faculty in 2016 as an Assistant Professor in the Department of Lab Medicine and Pathology.  Her research goal is to understand the molecular and biochemical mechanisms underlying age-related disorders, with a particular focus on neurodegenerative disorders.  She has developed human stem cell models to further this line of research, as […]

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